Steven Salzberg, Ph.D., Bloomberg Distinguished Professor of biomedical engineering, computer science, and biostatics; Director of the Center for Computational Biology at Johns Hopkins University
The Human Genome Project was launched with the promise of revealing all of our genes, the “code” that would help explain our biology. The publication of the human genome in 2001 provided only a very rough answer to this question. For more than a decade following, the number of protein-coding genes steadily shrank, but the introduction of RNA sequencing revealed a vast new world of splice variants and RNA genes. Dr. Salzberg will review where we’ve been and where we are today, and will describe the use of an unprecedentedly large RNA sequencing resource to create a comprehensive new human gene catalog, containing thousands of novel genes and gene variants.