Jill Barnholtz-Sloan, Ph.D.

Associate Director for Informatics and Data Science


As the Associate Director for Informatics and Data Science (IDS) Program, Dr. Jill Barnholtz-Sloan leads efforts at CBIIT to shape data science strategies and foster collaboration within NCI and across NIH and the cancer research community. She will also be actively pursuing a robust research agenda in descriptive epidemiology and etiology of brain tumors as an intramural NCI researcher in NCI’s Division of Cancer Epidemiology and Genetics (DCEG) Trans-Divisional Research Program. Blending these two unique perspectives—as an active researcher and as an administrator—gives her insight into how data can be translated into real-world solutions to help diagnose, prevent, and treat cancer.

Dr. Barnholtz-Sloan is a nationally and internationally recognized leader in the fields of cancer informatics and data science. As principal investigator of the Ohio Brain Tumor Study, a multi-site tissue source for The Cancer Genome Atlas and the Central Brain Tumor Registry for the United States (CBTRUS), she knows the challenges researchers face when collecting, integrating, analyzing, and sharing the full range of complex, multi-scale data in use today.

While at Case Western Reserve and University Hospitals Health System, she was the Sally S. Morley Designated Professor in Brain Tumor Research; associate director, Data Sciences at the Case Comprehensive Cancer Center; associate director, Translational Informatics, Cleveland Institute for Computational Biology; and director, Research Health Analytics and Informatics. This experience has given her a clear understanding of the administrative side of managing large, complex data sets. She’s successfully navigated issues related to data access, security, and privacy; and she’s implemented measures to make it easier for researchers to use data in ways that yield meaningful results.

Dr. Barnholtz-Sloan is renowned in the field. She serves or has served on national and international advisory boards and committees for numerous brain tumor foundations, study sections, and consortia. She is an associate editor for multiple peer-reviewed journals, including Neuro-Oncology, Journal of Neuro-Oncology, and JCO Cancer Clinical Informatics.

She received her doctorate in biostatistics from the University of Texas Health Science Center at Houston School of Public Health, a master’s degree in statistics from the University of Texas at Austin, and a bachelor’s degree in mathematics from the University of Florida.


  • Cancer Moonshot℠
  • Childhood Cancer Data Initiative (CCDI)
  • Imaging Data Commons
  • NCI Cancer Research Data Commons (CRDC)
  • NCI Data Commons Framework

Selected Publications

See a full list of publications.