Umit Topaloglu, Ph.D.
Clinical & Translational Research Informatics Branch Chief
- Center for Biomedical Informatics & Information Technology
- Informatics and Data Science Program
- Clinical & Translational Research Informatics Branch
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Current Role
Current Role
As Chief of the Clinical and Translational Research Informatics Branch, I oversee the biomedical informatics efforts for several NCI clinical research endeavors, including the NCI Precision Medicine Initiatives, the Clinical Trials Reporting Program, and the strategic roadmap development.
I’m also responsible for oversight of NCI’s Semantic Infrastructure (i.e., NCI Enterprise Vocabulary Services and the Cancer Data Standards Registry and Repository), which is crucial to enabling standards-based data sharing, real world evidence, and cancer research. Additionally, I provide data science expertise for these programs and collaborate closely with bioinformatics and data ecosystem initiatives.
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Projects
Projects
Cancer Data Standards Registry and Repository (caDSR)
Provides access to oncology research common data elements and forms.
Childhood Cancer Data Initiative (CCDI)
Develops means to collect and share childhood cancer data to learn from every child with cancer.
Enterprise Vocabulary Services
Provides terminology content and tools to code, analyze, and share cancer and biomedical research information.
Molecular Analysis for Therapy Choice (MATCH)
Enrolls patients to determine whether treating cancer based on their genome is effective.
National Clinical Trials Network (NCTN)
Provides the infrastructure for NCI-funded treatment and primary advanced imaging trials.
NCI Cancer Research Data Commons (CRDC)
Connects researchers with data sets and tools to analyze large- scale cancer research data in the cloud.
NCTN/NCORP Data Archive
Stores and shares datasets generated from NCTN and NCORP clinical trials.
Pediatric MATCH
Enrolls children, teens, and young adults to test precision medicine for childhood cancers.
Therapeutically Applicable Research to Generate Effective Treatments (TARGET)
Studies the genome of childhood cancers to guide the development of less toxic therapies. -
Publications
Publications
Featured Publications
Applying FHIR Genomics for Research—From Sequencing to Database. 2022 AMIA Informatics Summit, 2022.
Risk and Outcome of Breakthrough COVID-19 Infections in Vaccinated Patients with Cancer: Real-world Evidence from the National COVID Cohort Collaborative (N3C). ASCO Journal of Clinical Oncology, 2021.
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In the News
In the News
Hear from CBIIT’s Chief of the Clinical and Translational Research Informatics Branch as he gives advice on how to conduct a research project using data science and the value data science brings to supporting the cancer research community. -
Background
Background
Education
- Ph.D., Applied Science, University of Arkansas at Little Rock
- M.S., Electrical Engineering, Cukurova University (Turkey)
- B.S., Electrical Engineering, Cukurova University (Turkey)
Previous Work
- Co-Director, Bioinformatics Shared Resource, Wake Forest University School of Medicine (WFSoM)
- Associate Lead, Informatics Program, Wake Forest Clinical and Translational Science Institute, WFSoM
- Associate Director, Center for Biomedical Informatics, WFSoM
- Associate Professor, Cancer Biology and Biostatistics and Data Science Departments, WFSoM
- Associate Director of Informatics, Wake Forest Baptist Comprehensive Cancer Center, WFSoM
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My Team
My Team