Intramural Investigators Submitting Genomic Data

The following steps are general requirements; please work with your Program Officer, who is responsible to ensure the accuracy of the institutional certification and your designated GPA. For general questions, please contact the NCI Office of Data Sharing (

Submission Request Workflow

Infographic displaying 6 steps NCI intramural investigators must take to submit data to NCI repositories. From the top left, going to the right, the steps are: 1. Prepare and submit a data sharing plan (submit the plan with your project proprosal). 2. Submit Institutional certification with appropriate signatures to Program Officer or GPA. For studies generating genomic data from human subjects, submit your research protocl to the IRB who will review the institutional certification. Before you generate data

1. Prepare and Submit a Data Sharing Plan

Intramural Investigators: Submit your data sharing plan with your project proposal.

2. Submit Institutional Certification with Appropriate Signatures to Program Officer or Genomic Program Administrator (GPA)

Note: Interpretation must be based on the Institutional Review Board's interpretation of this document:

  • Human subjects research-submit research protocol to relevant Institutional GPA
  • De-identified human specimens research – submit a request for Office of Human Subjects Research Protections (OHSRP) determination

If disease-specific data uses or data-use modifiers are required, please contact the NCI Office of Data Sharing ( for clarification.

3. Generate Data 

Once data for the full genomic data set has been generated and cleaned, the investigators submits the Basic Study Information form describing the data set to:

4. QA/QC Data Before Submission

Submitting investigator performs appropriate QA/QC checks on the data and metadata, then Principal Investigator Assistant/Submitter uploads appropriate files to dbGaP to obtain a phs accession (obtaining a phs accession number can take up to 4-8 weeks).

5. Complete Full Data and Metadata Submission

  • If data going to GDC, then Principal Investigator/Grantee will need to contact the Genomic Data Commons Helpdesk for appropriate submission instructions.
  • If data going to NCBI and/or the Cancer Data Service (CDS), then PI/Grantee will follow dbGaP or CDS instructions.

NIH Repositories Data Set Release Expectations

dbGaP/NCI-approved repositories aim to release the data 6 months from the date of submission of a full, cleaned and quality-checked data set or at the time of first publication (whichever comes first).

For additional questions about submitting data to NCI and NIH Repositories, please contact the Office of Data Sharing (

NIH/NCI Genomic Data Repositories Help Resources

If you encounter difficulty submitting data to a particular repository, please contact these help resources directly.

Repositories Help Resources
Database of Genotypes and Phenotypes (dbGaP) dbGaP Contact Form
Genomic Data Commons (GDC) GDC Help Desk
Sequence Read Archive (SRA) SRA Help Desk
Other NCBI Data Repositories National Library of Medicine Help Desk


For additional questions about data sharing, please contact the NCI Office of Data Sharing.

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