Clinical Trials Reporting Program (CTRP)

About the CTRP

The Clinical Trials Reporting Program is a database for reporting information on NCI-funded (both direct and indirect funding) interventional clinical trials.

Using this database, you can:

  • identify gaps and duplicative studies in clinical research.
  • prioritize developing new clinical trials.
  • capture and share trial data in a standardized way.
  • more efficiently search and access cancer trial data thanks to CTRP’s consistent terminology and coding.
  • access structured biomarker data, patient-level accrual data, and standardized data elements.
  • ensure compliance with NCI clinical trial reporting requirements.
  • facilitate reporting of trial information to ClinicalTrials.gov.
  • provide a centralized database for all NCI-funded clinical trials.
  • support NCI’s mission to advance cancer research and improve patient outcomes.

NCI’s Role

NCI created CTRP in response to the NCI Clinical Trials Working Group’s report to the National Cancer Advisory Board. The report had three key findings, which focus on gaps in clinical trial searchability and identification.

NCI’s Center for Biomedical Informatics and Information Technology (CBIIT) collaborates with NCI’s Coordinating Center for Clinical Trials who manages CTRP by:

  • leading the development and maintenance of CTRP systems.
  • ensuring data integrity and quality by implementing robust data management practices.
  • managing technical architecture and security as well as technical best practices.
  • coordinating with researchers, clinicians, and regulatory bodies to deliver technical solutions to enhance systems.
  • overseeing compliance to ensure CTRP processes and data handling practices adhere to NIH (and other federal data systems) regulations.
  • guiding a team of developers, engineers, and analysts to build a collaborative environment within the project.
  • managing data integration from various sources so that all data are compatible and interoperable with other systems and databases.
  • promoting collaboration between CTRP and other teams both externally and within NCI.

Connecting the Cancer Community

You can access publicly available CTRP clinical trial information through an application programming interface (API). You can then use the information from the API to identify studies for clinical research solutions, including clinical trial matching. Another NCI-supported program—USCDI+ Cancer—is defining data elements for matching studies, and if you use clinical trial information from CTRP, those data elements should match.

Want to stay informed about the informatics and data science aspects of CTRP? Subscribe to weekly emails from CBIIT to ensure you get that kind of news (and more) straight to your inbox.

Additional Information

Whether you’re an NCI-designated Cancer Center staff member or a grantee, if you need a more detailed report from CTRP, email the Clinical Trials Reporting Office. An analyst will assist you with creating a custom report.

Need help registering or navigating the CTRP database? Explore NCI user guides and trouble-shooting resources.

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