The Center for Biomedical Informatics and Information Technology (CBIIT) mission is supported by the:
- Business Operations Branch (BOB)
- Informatics and Data Science (IDS) Program
- Infrastructure and Information Technology Operations Branch (IITOB)
- NCI Office of Data Sharing (ODS)
Business Operations Branch (BOB)
Branch Chief: Dwayne Forquer, M.B.A
The Business Operations Branch (BOB) provides essential business services and support for CBIIT by managing its business portfolio, financial and contract management, staffing, and communications. In addition to guiding CBIIT’s business practices, BOB fulfills CBIIT’s role to steward federal IT funding and data inquiries on behalf of NCI. BOB:
- coordinates timely and accurate information for NCI IT data calls from the U.S. Department of Health and Human Services (HHS), NIH, and the Office of Management and Budget
- establishes NCI processes to adhere to federal mandates for IT spending and compliance with the Federal Information Acquisition Reform Act (FITARA)
- manages CBIIT’s business portfolio to improve the efficiency of CBIIT’s service to NCI
Informatics and Data Science Program (IDS)
Associate Director: Tony Kerlavage, Ph.D. (Acting)
The IDS Program provides bioinformatics capabilities facilitating interoperability, collaboration, and integration across applications. This program provides centralized management and coordination for scientific software and training across NCI and computational biology services for intramural research labs. IDS also initiates and manages special projects and activities that further the use of informatics throughout the cancer research community and provides capabilities such as cloud computing, high-performance computing, and scientific collaboration tools.
Clinical & Translational Research Informatics Branch (CTRIB)
Branch Chief: Vacant
- provides informatics infrastructure and biomedical informatics expertise for key NCI Precision Medicine InitiativesSM such as the Molecular Analysis for Therapy Choice (NCI-MATCH), NCI-COG Pediatric MATCH, and other precision medicine trials
- provides informatics infrastructure and expertise to support the Clinical Trials Reporting Program, clinical data capture and management systems, and other NCI clinical research programs
- provides semantic resources, such as the NCI Enterprise Vocabulary Services (EVS) and the Cancer Data Standards Registry and Repository (caDSR), to enable standards-based data sharing and research
Data Ecosystems Branch (DEB)
Branch Chief: Allen Dearry, Ph.D.
- initiates and coordinates programs and activities to further the use of data and informatics tools throughout the cancer research community such as the Cancer Research Data Commons, specific cancer research data nodes, and the NCI Cloud Resources
- engages with international coordinating bodies, such as the GA4GH, to ensure adherence to the Findable, Accessible, Interoperable, and Reusable (FAIR) Data Principles
- provides collaboration resources for NCI and the cancer research community
- collaborates with other government agencies to advance informatics, high performance computing, and AI for cancer research (e.g., the Joint Design of Advanced Computing Solutions for Cancer collaboration with the DOE)
Computational Genomics & Bioinformatics Branch (CGBB)
Branch Chief: Daoud Meerzaman, Ph.D.
- provides advanced computational genomics data analysis, scientific consultation, and training to support both the intramural and extramural NCI scientific communities
- provides NCI researchers and fellows with the skills needed to learn how to select and use bioinformatics and computational-genomics tools to analyze, integrate, and interpret large data sets generated by next-generation sequencing platforms
Infrastructure and Information Technology Operations Branch (IITOB)
Branch Chief: Jeff Shilling
The Infrastructure and IT Operations Branch (IITOB) manages the IT infrastructure for the NCI enterprise. In addition to providing IT support to enable the work of the Institute daily, IITOB leads efforts to modernize and provide access to leading-edge technology and capabilities for NCI.
- plans and maintains institute-wide infrastructure including network resource, scientific and business data repositories, telecommunications, collaboration tools, and wireless devices
- maintains IT Security measures for NCI
- oversees IT operational security to ensure compliance with all relevant federal security plans, standards, and NIH-wide policies
- provides data protection, disaster recovery, and IT support
Office of Data Sharing (ODS)
Director: Jaime M. Guidry Auvil, Ph.D.
The NCI Office of Data Sharing (ODS), headquartered within the Center for Biomedical Informatics and Information Technology (CBIIT), is creating a comprehensive data sharing vision and strategy for NCI and the cancer research community.
The office advocates for the proper balance of open-access and broad data sharing policies to enable reproducibility, secondary use, and knowledge sharing. ODS respects the rights of the public to participate in and benefit from publicly funded research while considering the critical importance of intellectual property concerns for individuals and organizations to support a healthy commercial marketplace.
- advises on ethical data access and sharing issues, policies, and practices
- enhances the accessibility and utility of research data and metadata, in part by refining data and metadata standards
- develops sustainable, achievable, and meaningful incentives for data sharing
- supports equitable sharing through a robust, sustainable data ecosystem
- encourages participation in major data-sharing initiatives, including contributing to NIH data repositories
- creates educational resources to guide the cancer community on the importance and processes of sharing data