The Childhood Cancer Data Initiative (CCDI) focuses on the critical need to collect, analyze, and share data to address the burden of childhood cancer. This symposium is intended as a scientific planning session for the CCDI. NCI will convene approximately 250 scientific stakeholders and leaders from academia, government, industry, and advocacy in Washington, DC to gain a common understanding of the current issues and opportunities in childhood cancer research that can be addressed through enhanced data collection and maximum utilization.