Next-Generation Tools and Resources for Next-Generation Immunogenetic Data

November 05, 2021 12:00 p.m. - 1:00 p.m. ET

In an effort to consolidate the copious and heterogeneous data associated with the genetic variation of the Human Leukocyte Antigen (HLA) system (an important, polymorphic, and gene-dense region of the human genome), a team of scientists have developed a suite of standards, tools, and resources for analyzing, collecting, exchanging, and storing all current and future immunogenetic data. Dr. Jill Hollenbach, associate professor in the Department of Neurology at the University of California, San Francisco, will introduce these standards and resources. More specifically, she will address how this suite is designed to maximize the usability of these data for clinical and basic research science.

Over 100 infectious, autoimmune, and pharmacological disease phenotypes and cancers are associated with genetic variation of HLA. In the most successful application of precision medicine to date, HLA genotype matching is required for bone marrow and solid organ transplantation.

Jill A. Hollenbach, Ph.D., MPH

Dr. Hollenbach is an associate professor in the Department of Neurology at University of California, San Francisco.

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