GDC DNA-Seq Data Processing
This webinar is intended for cancer researchers and bioinformaticians who are interested in learning more about the NCI Genomic Data Commons’ (GDC’s) bioinformatics pipelines for data harmonization.
The GDC DNA-Seq analysis pipeline identifies somatic variants within whole exome sequencing (WXS) and whole genome sequencing (WGS) data. Somatic variants are identified by comparing allele frequencies in normal and tumor sample alignments, annotating each mutation, and aggregating mutations from multiple cases.
In this webinar, the University of Chicago’s Drs. Bill Wysocki and Zhenyu Zhang will:
- Provide an overview of the GDC DNA-Seq alignment workflows
- Review the GDC WXS somatic variant calling workflow
- Review the GDC WGS somatic variant calling, copy number variation, and structural variation workflows
- Demonstrate how to download DNA-Seq data generated from GDC workflows
Dr. Bill Wysocki is the director of user services at the University of Chicago.
Dr. Zhenyu Zhang is the lead bioinformatician for the GDC in the Center for Data Intensive Science (CDIS) at The University of Chicago.
Upcoming Events
- Predicting Patients’ Response to Immunotherapy from Tumor Histopathology and Blood: Computational Science in Immuno-oncologyJuly 08, 2025Assessing the Tumor Microenvironment with Systems Immunology: Computational Science in Immuno-oncologyAugust 21, 2025Data Jamboree: Enhancing Childhood Cancer Data Sharing and UtilitySeptember 29, 2025 - September 30, 2025NCI Office of Data Sharing’s Annual Data Sharing Symposium 2025: How Data Advances the Impact of Cancer ResearchSeptember 30, 2025 - October 01, 2025Childhood Cancer Data Initiative (CCDI) Symposium 2025October 06, 2025 - October 07, 2025