GDC DNA-Seq Data Processing
This webinar is intended for cancer researchers and bioinformaticians who are interested in learning more about the NCI Genomic Data Commons’ (GDC’s) bioinformatics pipelines for data harmonization.
The GDC DNA-Seq analysis pipeline identifies somatic variants within whole exome sequencing (WXS) and whole genome sequencing (WGS) data. Somatic variants are identified by comparing allele frequencies in normal and tumor sample alignments, annotating each mutation, and aggregating mutations from multiple cases.
In this webinar, the University of Chicago’s Drs. Bill Wysocki and Zhenyu Zhang will:
- Provide an overview of the GDC DNA-Seq alignment workflows
- Review the GDC WXS somatic variant calling workflow
- Review the GDC WGS somatic variant calling, copy number variation, and structural variation workflows
- Demonstrate how to download DNA-Seq data generated from GDC workflows
Dr. Bill Wysocki is the director of user services at the University of Chicago.
Dr. Zhenyu Zhang is the lead bioinformatician for the GDC in the Center for Data Intensive Science (CDIS) at The University of Chicago.
Upcoming Events
- Social Determinants of Health with Large/Moderate Language Models on EHR Data: AI in Immuno-oncologyJuly 30, 2024CCDI Federated Data: Enhancing Data DiscoverabilityAugust 13, 2024Leveraging High-Performance Computing Resources and Using QIIME 2 to Advance Your Microbiome ProjectsAugust 27, 2024 - August 29, 2024NCI Office of Data Sharing’s Annual Data Sharing Symposium: Driving Cancer Advances Through Impactful ResearchOctober 16, 2024The Cancer Research Data Commons 2024 Fall Symposium: Ten Years of Empowering Cancer ResearchersOctober 16, 2024 - October 17, 2024