Example Use Cases for Harmonized Data in the GDC
During this webinar, the Genomic Data Commons’ (GDC’s) Drs. Zhenyu Zhang and Bill Wysocki will review the different types of harmonized data that the GDC makes available for the cancer research community. The webinar will also:
- exemplify use cases for this data, such as how to:
- identify high- and low-frequency cancer drivers.
- define genomic determinants of response to therapy.
- inform the composition of clinical trial cohorts that shared targeted genetic lesions.
- provide an overview of GDC pipelines for harmonizing and processing data.
The NCI GDC harmonizes raw sequencing data from cancer genomic studies by aligning to a common reference genome and applying standard bioinformatics pipelines. This generates high-level data such as mutation calls and structural variants.
As part of the NCI Cancer Research Data Commons (CRDC), the GDC provides the cancer research community with data and tools to access, analyze, and share valuable genomic data.
Dr. Wysocki is the director of User Services and Outreach for the GDC at the University of Chicago.
Dr. Zhang is the GDC co-principal investigator at the University of Chicago.
Upcoming Events
- Social Determinants of Health with Large/Moderate Language Models on EHR Data: AI in Immuno-oncologyJuly 30, 2024CCDI Federated Data: Enhancing Data DiscoverabilityAugust 13, 2024Leveraging High-Performance Computing Resources and Using QIIME 2 to Advance Your Microbiome ProjectsAugust 27, 2024 - August 29, 2024NCI Office of Data Sharing’s Annual Data Sharing Symposium: Driving Cancer Advances Through Impactful ResearchOctober 16, 2024The Cancer Research Data Commons 2024 Fall Symposium: Ten Years of Empowering Cancer ResearchersOctober 16, 2024 - October 17, 2024