Computational Science in Immuno-Oncology: Multiplex Imaging for Biomarker Development

In partnership with NCI’s Cancer Moonshot^SM Initiative, the Society for Immunotherapy of Cancer (SITC) and the Big Data and Data Sharing Committee are hosting the sixth of nine webinars that make up the 2022 SITC-NCI Computational Immuno-Oncology Webinar Series. Dr. Janis Taube of Johns Hopkins School of Medicine will present, “Multiplex Imaging for Biomarker Development: Computational Science in Immuno-Oncology” with moderation by Dr. Riyue Bao of the Hillman Cancer Center at the University of Pittsburgh Medical Center (UPMC).

The next generation of biomarkers for immuno-oncology are likely to include those with a spatial component. During this session, Dr. Taube will discuss:

• her work on recently developing an end–to-end pipeline for multiplex immunofluorescence protein expression mapping across the tumor microenvironment with high-fidelity, single cell resolution.
• the lessons learned at each stage in the workflow.
• key computational questions.

The SITC-NCI Computational Immuno-Oncology Webinar Series consists of nine, hour-long courses featuring a moderator and faculty speaker to lead instruction. Topics will cover a host of computational challenges of analyzing and integrating diverse assay data across the spectrum of immuno-oncology. This series is intended for scientists early in their career and/or those who want to remain abreast of the latest technologies. These webinars were created to foster better communication concerning data science technologies and analyses between cancer immunotherapy researchers and clinicians to advance translational immunotherapy research.