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New Lung Squamous Cell Carcinoma Data in the NCI Proteomics Data Commons (PDC)

Supplementary proteomics data from the most comprehensive molecular map of lung squamous cell carcinoma (LSCC) is available in the NCI Proteomics Data Commons (PDC).

As described in their recent Cell article, researchers from the NCI Clinical Proteomics Tumor Analysis Consortium (CPTAC), the Broad Institute of MIT, and Harvard, collectively brought together proteomic, transcriptomic, and genomic data to develop the largest proteogenomic view of LSCC to date.

The data set includes the following experimental methods from 108 patients:

  • Whole proteome
  • Phosphoproteome
  • Acetylproteome
  • Ubiquitylproteome

Interested cancer researchers and data scientists can access these files directly from the PDC portal or through the NCI Cloud Resources. Whole genome, whole exome, RNA, and microRNA data sequencing data is available through the Genomic Data Commons (GDC). This includes processed data, such as gene expression and copy number variations.

As a component of the Cancer Research Data Commons, the PDC connects researchers with large-scale proteomics data and the high-performance computational tools to analyze that data. For more information on the data and tools you can find in the PDC, visit the Data Commons website.