NCI’s National Clinical Trials Network (NCTN) released the largest known data set that includes patients with supratentorial primitive neuroectodermal tumors (PNET) and pineoblastoma. These tumors are defined by their appearance and are thought to develop from undeveloped nerve cells in the brain. The data set provides imaging of pediatric patients with newly diagnosed PNET throughout their treatment and until any potential relapse.

The new data comes from the study, “Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET.” This study looked at different chemotherapy and radiation therapy treatments to compare how well they work in treating young patients with newly diagnosed, previously untreated, high-risk medulloblastoma.

The data set is limited access* and includes:

• “ACNS0332 Annotations—Segmentations, Seed Points, and Negative Findings Assessments.”
• “ACNS0332 Annotation Metadata.”
• “Original ACNS0332 Images used to create Segmentations and Seed Points.”
• “Original ACNS0332 Images used to create Negative Assessment reports.”

Some of the data types require the National Biomedical Imaging Archive Data Retriever for download.

*To request access to the imaging data and annotations, you can register for an account on the NCTN Data Archive.