Cancer Genomics to Identify Novel Biomarkers and Drivers and to Enable Precision Therapeutics
Dr. Javed Khan, Deputy Chief of NCI's Genetics Branch and Senior Investigator and Head of the Oncogenomics Section, will discuss the following:
- Success and Challenges of Treating Pediatric Cancers.
- Biomarkers, Drivers, and Therapeutic Targets
- Using first Generation Genomics to identify biologically relevant therapeutic targets
- Next generation genomics of pediatric cancers
- Tumor heterogeneity
- Next Generation Therapeutics: Personalized Therapies and Immunogenomics
- Enabling Precision Therapy Trials in CCR
Dr. Javed Khan obtained his bachelor's degree in 1984 and his master's degrees in 1989 in immunology and parasitology at England's University of Cambridge. He subsequently obtained his M.D. there and the postgraduate degree of MRCP (Membership of the Royal College of Physicians), equivalent to board certification in the United States. After clinical training in internal medicine and pediatrics as well as other specialties, he received a Leukemia Research Fellowship. In May 2001, Dr. Khan joined the Pediatric Branch, NCI, as a tenure track investigator. Dr. Khan and colleagues have published a new model for diagnosis of cancer using artificial neural networks (ANN), a form of artificial intelligence, and microarray technology. In April 2001, Dr. Khan was recognized by the American Association for Cancer Research for his work in tumor profiling by receiving a Scholar in Training Award. Recently Dr. Khan has led an international collaboration to perform comprehensive analysis of pediatric cancer genomes using next generation sequencing strategies.