Cancer Data Science Pulse

Learn more about the Genomic Data Commons

NCI has launched the Genomic Data Commons (GDC), a system that will promote sharing of genomic and clinical data between researchers and facilitate precision medicine in oncology. The GDC was created to centralize, standardize, and broaden access to data from NCI programs such as The Cancer Genome Atlas (TCGA) and its pediatric equivalent, Therapeutically Applicable Research to Generate Effective Treatments (TARGET).

National Cancer Institute Genomic Data Commons infographic. Header reads: "The NCI Genomic Data Commons (GDC) is a knowledge base for cancer that promotes sharing of genomic and clinical data between researchers and facilitates precision medicine in oncology." Below is a timeline of GDC events. Timeline point 1: The GDC brings together harmonized genomic datasets, starting with 3 petabytes of NCI genomic data from TCGA and other initiatives. Timeline point 2: Researchers are encouraged to submit their data.

The GDC went live on June 6, with approximately 4.1 petabytes of data from TCGA, TARGET, and other research programs, as well as more than 14,000 anonymized patient cases. In addition to the TCGA and TARGET data, the GDC will accept submissions of cancer genomic and clinical data from researchers around the world who wish to share their data broadly.

These datasets will provide researchers with the opportunity to investigate what therapies are most effective for the specific mutations that cause cancer, and focus on individual cancer patients. As the GDC grows, it will become the foundation of a knowledge system that will enable discovery and improve the success of cancer treatments. 

Vice President Joseph Biden has emphasized the importance of enhanced data sharing as part of the Administration's National Cancer Moonshot Initiative. The GDC represents one of NCI's significant commitments towards this goal.

The GDC is being built and managed by the University of Chicago Center for Data Intensive Science, in collaboration with the Ontario Institute for Cancer Research under an NCI contract with Leidos Biomedical Research in Frederick, Maryland.

You can learn more at:

Project Manager, Cancer Informatics Branch, CBIIT
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